Although the clinical value of endothelial testing has been demonstrated as a key biomarker of atherosclerosis and coronary heart disease, current diagnostic testing methods (such as Brachial Artery Ultrasound, ‘BAUI’) are costly, difficult and complex to use.
The BAUI method has major limitations; it requires access to expensive ultrasound equipment, a specialized ultrasound probe and a highly trained technician. Brachial artery ultrasound is highly dependent on the skill of the individual technician and varies greatly from one user to the next. Consequently, the cost, complexity and time required to perform ultrasound based measurement of Flow Mediated Dilation (‘FMD’) of the brachial artery has confined its use to research applications.