Everist Genomics Blog

Microsatellite Instability in Determining Adjuvant Chemotherapy Sensitivity and Drug Selection MSI (Third in a series)

Microsatellites are repeated sequences that are distributed throughout the genome.  When microsatellites are copied incorrectly, the Mismatch Repair (MMR) system ensures surveillance and correction of these errors and ensures microsatellite stability.  Defects in the MMR system lead to microsatellite instability … Continue reading →